Comparison of Semi-automated Late Gadolinium Enhancement Quantification Techniques in Measuring Septal Fibrosis in Patients with Dilated Non-Ischemic Cardiomyopathy
نویسندگان
چکیده
Background Mid-wall striae pattern late gadolinium enhancement (LGE) has been shown to independently predict future outcomes in patients with dilated non-ischemic cardiomyopathy (NICM). Standardized quantification tools are of particular interest for clinical translation of this novel imaging marker. However, signal intensity (SI) based threshold techniques, such as Signal Threshold versus Reference Mean (STRM) and Full Width at Half Maximum (FWHM), have been inconsistently applied and their performance in this population is unknown. The purpose of this study was to compare the accuracy of semi-automated LGE quantification techniques against expert-prescribed threshold assignment in patients with NICM.
منابع مشابه
Prognostic significance of the extent of septal fibrosis quantified on late gadolium enhanced images in patients with nonischemic cardiomyopathy
Background Midwall septal fibrosis on late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging has been shown to be an independent predictor of adverse events in patients with non-ischemic dilated cardiomyopathy (NICM). Recent studies in other cardiomyopathy cohorts, such as Hypertrophic Cardiomyopathy, suggest that LGE extent provides incremental prognostic value over ...
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